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Cerebral White Matter Hyperintensities on MRI: Current Concepts and Therapeutic Implications
Author(s) -
Bruce Ovbiagele,
Jeffrey L. Saver
Publication year - 2006
Publication title -
cerebrovascular diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.221
H-Index - 104
eISSN - 1421-9786
pISSN - 1015-9770
DOI - 10.1159/000093235
Subject(s) - medicine , hyperintensity , white matter , stroke (engine) , magnetic resonance imaging , population , intensive care medicine , neuroscience , radiology , psychology , mechanical engineering , engineering , environmental health
White matter hyperintensities (WMH) are commonly observed MRI abnormalities in the elderly, which generally reflect covert vascular brain injury. WMH cumulatively produce substantial neurologic, psychiatric, and medical morbidity. This review provides an overview of current knowledge on vascular WMH, and describes some pharmacological agents that may have a role in mitigating this condition.

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