The ScanGel System Shows at least Equal Sensitivity for the Detection of Red Cell Antibodies in Comparison to the ID Micro Typing System | Zendy

V. Kretschmer | Zendy; Karin Schmidt | Zendy; Monika Bornmann | Zendy; Ralf Karger | Zendy

Open Access

The ScanGel System Shows at least Equal Sensitivity for the Detection of Red Cell Antibodies in Comparison to the ID Micro Typing System

Author(s) -

V. Kretschmer,

Karin Schmidt,

Monika Bornmann,

Ralf Karger

Publication year - 2006

Publication title -

transfusion medicine and hemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 39

eISSN - 1660-3818

pISSN - 1660-3796

DOI - 10.1159/000091347

Subject(s) - typing , serology , blood typing , red cell , red blood cell , antibody , medicine , immunology , biology , microbiology and biotechnology

Objective: The aim of this study was to compare 2 test systems for red cell antibody screening. Materials and Methods: 30 fresh and 92 stored frozen samples with known red cell antibodies (rbc-abs) and 356 consecutive blood samples sent in for routine serology were investigated in parallel using 2 different test systems: the ID Micro Typing System (test system A) and the ScanGel System (test system B). Results: Test system B demonstrated a significantly higher sensitivity (98.4 vs. 91.0%, p = 0.019) and equal specificity (99.7 vs. 100%) compared to test system A. Conclusion: In this study, the ScanGel System was at least as good as the ID Micro Typing System in the detection of rbc-abs. It showed a significantly higher sensitivity that will have to be confirmed in prospective studies and across different batches of test cells.

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