Open AccessGenetic Studies of IgA Nephropathy
Author(s) -
Patrick H. Maxwell,
Yiming Wang
Publication year - 2005
Publication title -
nephron experimental nephrology
Language(s) - English
Resource type - Journals
ISSN - 1660-2129
DOI - 10.1159/000089685
Subject(s) - nephropathy , pedigree chart , pathogenesis , glomerulonephritis , kidney disease , disease , biology , immunology , medicine , genetics , kidney , pathology , gene , endocrinology , diabetes mellitus
IgA nephropathy is the commonest form of glomerulonephritis worldwide, but we still know relatively little about its pathogenesis. Potentially, genetic studies might provide new insights and suggest novel therapeutic approaches to this important cause of chronic kidney disease. Two approaches that are likely to yield new information are analysis of multiply affected pedigrees and large-scale, well-controlled association studies.
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