Open AccessModulation of the Transforming Growth Factor β1 by Vitamin E in Early Nephropathy
Author(s) -
C. Cojocel,
May AlMaghrebi,
Martha Thomson,
Parvez Rawoot,
Raj Raghupathy
Publication year - 2005
Publication title -
medical principles and practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 45
eISSN - 1423-0151
pISSN - 1011-7571
DOI - 10.1159/000088116
Subject(s) - endocrinology , medicine , streptozotocin , malondialdehyde , diabetic nephropathy , renal cortex , excretion , diabetes mellitus , fructosamine , kidney , oxidative stress
The aim of this study was to investigate the pharmacological activity of an antioxidant, alpha-tocopherol (vitamin E, VE) in streptozotocin-induced diabetic rats and study its role in modulating the transforming growth factor beta1 (TGF-beta1).
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