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Cells on a Chip - the Use of Electric Properties for Highly Sensitive Monitoring of Blood-Derived Factors Involved in Angiotensin II Type 1 Receptor Signalling
Author(s) -
Andrée Rothermel,
Randy Kurz,
Markus Rüffer,
W Weigel,
HeinzGeorg Jahnke,
Anna Sedello,
Holger Stepan,
R Faber,
Kai SchulzeForster,
Andrea A. Robitzki
Publication year - 2005
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000087731
Subject(s) - receptor , chronotropic , angiotensin ii receptor type 1 , angiotensin ii , angiotensin receptor , medicine , biology , microbiology and biotechnology , endocrinology , chemistry , blood pressure , heart rate
We developed a highly sensitive cardiomyocyte based screening system for the non-destructive electronic detection of chronotropic drugs and tissue-secreted factors involved in AT1 receptor-mediated cardiovascular diseases.

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