On the Pharmacotherapy of Sleep Bruxism: Placebo-Controlled Polysomnographic and Psychometric Studies with Clonazepam
Author(s) -
A. Saletu,
Silvia Parapatics,
B. Saletu,
P. Anderer,
Wolfgang Prause,
Hanna Putz,
Josef Adelbauer,
G. SaletuZyhlarz
Publication year - 2005
Publication title -
neuropsychobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.71
H-Index - 83
eISSN - 1423-0224
pISSN - 0302-282X
DOI - 10.1159/000085917
Subject(s) - polysomnography , clonazepam , pittsburgh sleep quality index , epworth sleepiness scale , placebo , anxiety , psychology , insomnia , restless legs syndrome , sleep bruxism , physical therapy , medicine , anesthesia , psychiatry , electromyography , electroencephalography , alternative medicine , pathology , sleep quality
Sleep bruxism (SB) is a parasomnia defined as a stereotyped movement disorder characterized by grinding or clenching of the teeth during sleep. Pathophysiologically, SB is the result of biological and psychosocial influences. Treatment comprises behavioral, orthodontic and pharmacological interventions. While benzodiazepines and muscle relaxants have been reported by clinicians to reduce bruxism-related motor activity, placebo-controlled studies are lacking. Thus, the aim of the present study was to investigate the acute effects of clonazepam (Rivotril) as compared with placebo, utilizing polysomnography and psychometry.
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