HLA-DR Binding Prediction and Experimental Evaluation of T-Cell Epitopes of Mycolyl Transferase 85B (Ag85B), a Major Secreted Antigen of <i>Mycobacterium tuberculosis</i>
Author(s) -
Abu Salim Mustafa,
Adnan T. Abal,
Fatma Shaban,
Abdulsalam M. El-Shamy,
Hanady A. Amoudy
Publication year - 2005
Publication title -
medical principles and practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 45
eISSN - 1423-0151
pISSN - 1011-7571
DOI - 10.1159/000084629
Subject(s) - human leukocyte antigen , allele , epitope , antigen , microbiology and biotechnology , t cell , peripheral blood mononuclear cell , biology , immunology , genetics , gene , in vitro , immune system
To identify T-cell epitopes of Ag85B by analysis of its sequence for prediction to bind HLA-DR alleles and evaluate the predicted peptides for recognition by T cells in antigen-induced proliferation assays.
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