Extended Single Nucleotide Polymorphism and Haplotype Analysis of the elastin Gene in Caucasians with Intracranial Aneurysms Provides Evidence for Racially/Ethnically Based Differences | Zendy

Dietmar Krex | Zendy; Inke R. König | Zendy; Andreas Ziegler | Zendy; Hans K. Schackert | Zendy; Gabriele Schackert | Zendy

Open Access

Extended Single Nucleotide Polymorphism and Haplotype Analysis of the <i>elastin</i> Gene in Caucasians with Intracranial Aneurysms Provides Evidence for Racially/Ethnically Based Differences

Author(s) -

Dietmar Krex,

Inke R. König,

Andreas Ziegler,

Hans K. Schackert,

Gabriele Schackert

Publication year - 2004

Publication title -

cerebrovascular diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.221

H-Index - 104

eISSN - 1421-9786

pISSN - 1015-9770

DOI - 10.1159/000079257

Subject(s) - single nucleotide polymorphism , elastin , haplotype , genetics , allele , locus (genetics) , genotype , population , phenotype , snp , gene , genetic association , allele frequency , medicine , biology , polymorphism (computer science) , environmental health

There is growing evidence that genetic variants have an impact on the pathogenesis of intracranial aneurysm (IA). Recently, the genetic locus around the elastin gene (7q11) has been identified as linked to IA in a Japanese population. Our aim was to confirm these results in Caucasian populations.

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