Amniotic Fluid Embolism with Haemostasis Complications: Primary Fibrinogenolysis or Disseminated Intravascular Coagulation? | Zendy

Christine BironAndréani | Zendy; Estelle Morau | Zendy; JeanFrançois Schved | Zendy; B. Hédon | Zendy; H. Déchaud | Zendy

Open Access

Amniotic Fluid Embolism with Haemostasis Complications: Primary Fibrinogenolysis or Disseminated Intravascular Coagulation?

Author(s) -

Christine BironAndréani,

Estelle Morau,

JeanFrançois Schved,

B. Hédon,

H. Déchaud

Publication year - 2003

Publication title -

pathophysiology of haemostasis and thrombosis

Language(s) - English

Resource type - Journals

eISSN - 1424-8840

pISSN - 1424-8832

DOI - 10.1159/000077826

Subject(s) - amniotic fluid embolism , disseminated intravascular coagulation , medicine , coagulation , amniotic fluid , coagulopathy , embolism , coagulation disorder , hypofibrinogenemia , thrombosis , fibrinogen , surgery , pregnancy , fetus , genetics , biology

Amniotic fluid embolism (AFE) is characterized by the passage of amniotic fluid (AF) into the maternal circulation during or just after childbirth. AFE is a rare disorder occurring in 1/8,000 to 1/80,000 deliveries but with a maternal morbidity ranging from 26% in a recent report to 86% in earlier ones. In patients who survive, AFE may affect coagulation resulting in severe bleeding. While disseminated intravascular coagulation (DIC) is usually seen in such cases, we reported a case of AFE in which the hemostatic abnormalities were compatible with primary fibrinogenolysis rather than with DIC.

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