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Inhibition of Ras-GTPase Improves Diabetes-Induced Abnormal Vascular Reactivity in the Rat Perfused Mesenteric Vascular Bed
Author(s) -
Mariam H.M. Yousif,
Ibrahim F. Benter,
Saju Abraham,
Saghir Akhtar
Publication year - 2004
Publication title -
medical principles and practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 45
eISSN - 1423-0151
pISSN - 1011-7571
DOI - 10.1159/000075629
Subject(s) - medicine , endocrinology , vasodilation , agonist , carbachol , small gtpase , signal transduction , diabetes mellitus , gtpase , vasoconstriction , mesenteric arteries , receptor , biology , microbiology and biotechnology , artery
The signalling mechanisms involved in regulating altered vascular reactivity in diabetes are not fully understood. The aim of this study was to investigate the role of Ras-GTPase in the development of abnormal vascular reactivity in diabetes.

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