Leukocyte CD15 Expression and Platelet Activation in the Coronary Sinus after Coronary Intervention | Zendy

Ursula Rauch | Zendy; Ursula Maria Wolff | Zendy; HeinzPeter Schultheiss | Zendy; Peter Schwimmbeck | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Leukocyte CD15 Expression and Platelet Activation in the Coronary Sinus after Coronary Intervention

Author(s) -

Ursula Rauch,

Ursula Maria Wolff,

HeinzPeter Schultheiss,

Peter Schwimmbeck

Publication year - 2003

Publication title -

pathophysiology of haemostasis and thrombosis

Language(s) - English

Resource type - Journals

eISSN - 1424-8840

pISSN - 1424-8832

DOI - 10.1159/000073855

Subject(s) - restenosis , medicine , coronary sinus , cardiology , coronary artery disease , platelet , adhesion , percutaneous coronary intervention , flow cytometry , cell adhesion molecule , cd15 , myocardial infarction , stent , immunology , stem cell , biology , chemistry , cd34 , organic chemistry , genetics

Markers associated with coronary restenosis must be identified to develop therapeutic strategies for improving the clinical outcome. We studied whether adhesion proteins on leukocytes and platelets from coronary sinus blood were associated with restenosis after coronary intervention in patients with stable coronary artery disease. Adhesion proteins on platelets and leukocytes were measured by flow cytometry. Pre- and postinterventional leukocyte CD15 expression was significantly higher in patients with restenosis than in those without it. Increased leukocyte CD15 expression during the intervention may contribute to coronary restenosis. Inhibition of leukocyte adhesion may be useful for the prevention of restenosis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research