Value and limitation of meta-analysis | Zendy

M Verstraete | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Value and limitation of meta-analysis

Author(s) -

M Verstraete

Publication year - 2002

Publication title -

pathophysiology of haemostasis and thrombosis

Language(s) - English

Resource type - Journals

eISSN - 1424-8840

pISSN - 1424-8832

DOI - 10.1159/000073581

Subject(s) - meta analysis , protocol (science) , clinical trial , publication bias , value (mathematics) , missing data , medicine , selection (genetic algorithm) , computer science , data mining , alternative medicine , artificial intelligence , pathology , machine learning

Meta-analysis is a valuable method of aggregating data sets of different trials which are inadequate or unconvincing on their own. There are strict rules on the retrieval and selection of data which are crucial in terms of the validity of a meta-analysis. Many so-called meta-analyses are flawed because of lack of a protocol or non adherence to it. Also underreporting of clinical trials is haunting the validity of meta-analysis. This hidden information is not a random process but is affecting mainly trials with negative results. To avoid this publication bias all clinical trials should enter an international online database.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research