Open AccessLate Onset of Diabetic Nephropathy in Spontaneously Diabetic GK Rats
Author(s) -
Nahoko Sato,
Koji Komatsu,
Hajimu Kurumatani
Publication year - 2003
Publication title -
american journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 85
eISSN - 1421-9670
pISSN - 0250-8095
DOI - 10.1159/000072915
Subject(s) - medicine , endocrinology , glomerulosclerosis , nephropathy , diabetic nephropathy , diabetes mellitus , renal function , kidney , fibrosis , urinary system , proteinuria
Prolonged exposure to hyperglycemia is one of the key factors to induce progressive diabetic nephropathy in humans. We examined whether or not the same phenomenon is observed in a nonobese type 2 diabetes model, in Goto-Kakizaki (GK) rats.
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