Why Thrombin Generation? From Bench to Bedside | Zendy

Louis M. Aledort | Zendy

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Why Thrombin Generation? From Bench to Bedside

Author(s) -

Louis M. Aledort

Publication year - 2003

Publication title -

pathophysiology of haemostasis and thrombosis

Language(s) - English

Resource type - Journals

eISSN - 1424-8840

pISSN - 1424-8832

DOI - 10.1159/000071635

Subject(s) - hemostasis , bench to bedside , thrombin generation , medicine , thrombin , thrombosis , intensive care medicine , intervention (counseling) , surgery , bioinformatics , immunology , medical physics , platelet , biology , psychiatry

Intervention for clotting and bleeding disorders is costly, and clear-cut regimens undefined. The margin of safety between hemostasis and thrombosis is narrow and unpredictable. The use of a laboratory test to help define therapeutic regimens, dissect effects of these treatments, and to differentiate them are clearly needed. The current state of the art of thrombin generation is ready to do this.

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