Decreased Trigeminal Sensitivity in Anosmia | Zendy

H. Gudziol | Zendy; Michael Schubert | Zendy; Thomas Hummel | Zendy

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Decreased Trigeminal Sensitivity in Anosmia

Author(s) -

H. Gudziol,

Michael Schubert,

Thomas Hummel

Publication year - 2001

Publication title -

orl

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.481

H-Index - 44

eISSN - 1423-0275

pISSN - 0301-1569

DOI - 10.1159/000055713

Subject(s) - anosmia , medicine , trigeminal nerve , olfactory system , etiology , disease , anesthesia , covid-19 , psychiatry , infectious disease (medical specialty)

The present study aimed to investigate intranasal trigeminal sensitivity in a large sample of patients with anosmia due to different etiologies. We investigated the trigeminal detection threshold for formic acid in healthy controls (n = 96) and patients with anosmia due to head trauma (n = 18) or sinonasal disease (n = 54). Anosmics exhibited higher thresholds compared with normosmics (p < 0.001). In addition, thresholds were found to be higher in patients with posttraumatic anosmia compared to anosmics with sinonasal disease (p < 0.001). The data indicate that (1) loss of olfactory sensitivity in humans may be associated with a decreased sensitivity towards trigeminal stimuli and (2) alteration of intranasal trigeminal function is stronger in patients with posttraumatic anosmia compared to patients with sinonasal disease. This may have implications for the medicolegal investigation of anosmic patients where trigeminal stimuli are frequently used to assess the patient's response bias.

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