Adequate Management of Heparin-Associated Thrombocytopenia
Author(s) -
Karl-Georg Fischer,
P. Schollmeyer
Publication year - 1997
Publication title -
the nephron journals/nephron journals
Language(s) - English
Resource type - Journals
eISSN - 2235-3186
pISSN - 1660-8151
DOI - 10.1159/000044890
Subject(s) - medicine , heparin , heparin induced thrombocytopenia , platelet , renal replacement therapy , hemofiltration , intensive care medicine , surgery , hemodialysis
In a recent issue of Nephron Berlot and Lucchese [1] reported their management of heparin-associated thrombocytopenia (HAT) during continuous venovenous hemofiltration. They described a case of rapid onset of severe thrombocytopenia after initiating intravenous heparin therapy and stated ‘that the diagnostic criteria for HAT have been completely fulfilled’. Despite of that, they reported a continuation of heparin therapy at lower doses without recovery of platelet counts at that stage and at last the slow return of platelet counts into the normal range more than 1 week after finishing intravenous heparin therapy. With reference to the current literature and the clinical experience in our hospital, this approach does not seem to be adequate.
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