The Use of Serial Circulating Tumor DNA to Detect Resistance Alterations in Progressive Metastatic Breast Cancer
Author(s) -
Saya Jacob,
Andrew A. Davis,
Lorenzo Gerratana,
Marko Velimirovic,
Ami N. Shah,
Firas Wehbe,
Neelima Katam,
Qiang Zhang,
Lisa Flaum,
Kalliopi P. Siziopikou,
Leonidas C. Platanias,
William J. Gradishar,
Amir Behdad,
Aditya Bardia,
Massimo Cristofanilli
Publication year - 2021
Publication title -
clinical cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.427
H-Index - 324
eISSN - 1557-3265
pISSN - 1078-0432
DOI - 10.1158/1078-0432.ccr-20-1566
Subject(s) - metastatic breast cancer , medicine , breast cancer , cancer , circulating tumor dna , pathology , oncology , cancer research
Circulating tumor DNA (ctDNA) is a promising tool for noninvasive longitudinal monitoring of genomic alterations. We analyzed serial ctDNA to characterize genomic evolution in progressive metastatic breast cancer.
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