Open AccessStroma, Stroma Everywhere (Far More Than You Think)
Author(s) -
Kenneth P. Olive
Publication year - 2015
Publication title -
clinical cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.427
H-Index - 324
eISSN - 1557-3265
pISSN - 1078-0432
DOI - 10.1158/1078-0432.ccr-15-0416
Subject(s) - stroma , stromal cell , pathology , biology , medicine , immunohistochemistry
Pancreatic ductal adenocarcinomas with high stromal content are shown to have greatly reduced overall survival, consistent with previous reports that stroma may limit drug delivery. In contrast to expectations, metastatic lesions were found to harbor as much stroma as primary tumors.
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