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Cetuximab-Based Immunotherapy and Radioimmunotherapy of Head and Neck Squamous Cell Carcinoma
Author(s) -
Gang Niu,
Xilin Sun,
Qizhen Cao,
Donald Courter,
Albert C. Koong,
QuynhThu Le,
Sanjiv S. Gambhir,
Xiaohong Chen
Publication year - 2010
Publication title -
clinical cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.427
H-Index - 324
eISSN - 1557-3265
pISSN - 1078-0432
DOI - 10.1158/1078-0432.ccr-09-2495
Subject(s) - cetuximab , head and neck squamous cell carcinoma , radioimmunotherapy , medicine , epidermal growth factor receptor , cancer research , immunotherapy , head and neck cancer , cancer , pathology , antibody , monoclonal antibody , colorectal cancer , immunology
To show the relationship between antibody delivery and therapeutic efficacy in head and neck cancers, in this study we evaluated the pharmacokinetics and pharmacodynamics of epidermal growth factor receptor (EGFR)-targeted immunotherapy and radioimmunotherapy by quantitative positron emission tomography (PET) imaging.

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