Predicting Relapse in Favorable Histology Wilms Tumor Using Gene Expression Analysis: A Report from the Renal Tumor Committee of the Children's Oncology Group | Zendy

ChiangChing Huang | Zendy; Samantha Gadd | Zendy; Norman E. Breslow | Zendy; Colleen Cutcliffe | Zendy; Simone Treiger Sredni | Zendy; Irene Helenowski | Zendy; Jeffrey S. Dome | Zendy; Paul E. Grundy | Zendy; Daniel M. Green | Zendy; Michael K. Fritsch | Zendy; Elizabeth J. Perlman | Zendy

Open Access

Predicting Relapse in Favorable Histology Wilms Tumor Using Gene Expression Analysis: A Report from the Renal Tumor Committee of the Children's Oncology Group

Author(s) -

ChiangChing Huang,

Samantha Gadd,

Norman E. Breslow,

Colleen Cutcliffe,

Simone Treiger Sredni,

Irene Helenowski,

Jeffrey S. Dome,

Paul E. Grundy,

Daniel M. Green,

Michael K. Fritsch,

Elizabeth J. Perlman

Publication year - 2009

Publication title -

clinical cancer research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.427

H-Index - 324

eISSN - 1557-3265

pISSN - 1078-0432

DOI - 10.1158/1078-0432.ccr-08-1030

Subject(s) - wilms' tumor , renal tumor , medicine , oncology , histology , pathology , kidney , nephrectomy

The past two decades has seen significant improvement in the overall survival of patients with favorable histology Wilms tumor (FHWT); however, this progress has reached a plateau. Further improvements may rely on the ability to better stratify patients by risk of relapse. This study determines the feasibility and potential clinical utility of classifiers of relapse based on global gene expression analysis.

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