Acrylamide and Glycidamide Hemoglobin Adducts and Epithelial Ovarian Cancer: A Nested Case–Control Study in Nonsmoking Postmenopausal Women from the EPIC Cohort | Zendy

Mireia ObónSantacana | Zendy; Leila LujánBarroso | Zendy; Ruth C. Travis | Zendy; Heinz Freisling | Zendy; Pietro Ferrari | Zendy; Gianluca Severi | Zendy; Laura Baglietto | Zendy; MarieChristine BoutronRuault | Zendy; Renée T. Fortner | Zendy; Jennifer Ose | Zendy; Heiner Boeing | Zendy; Virginia Menéndez | Zendy; Emilio SánchezCantalejo | Zendy; Saioa Chamosa | Zendy; José María Huerta | Zendy; Eva Ardanáz | Zendy; KayTee Khaw | Zendy; Nicholas J. Wareham | Zendy; Melissa A. Merritt | Zendy; Marc J. Gunter | Zendy; Antonia Trichopoulou | Zendy; EleniMaria Papatesta | Zendy; Eleni Klinaki | Zendy; Calogero Saieva | Zendy; Giovanna Tagliabue | Zendy; ­Rosario ­Tumino | Zendy; Carlotta Sacerdote | Zendy; Amalia Mattiello | Zendy; H. B. Bueno-de-Mesquita | Zendy; Petra H. Peeters | Zendy; N. Charlotte OnlandMoret | Zendy; Annika Idahl | Zendy; Eva Lundin | Zendy; Elisabete Weiderpass | Zendy; Hubert W. Vesper | Zendy; Elio Ríboli | Zendy; Eric J. Duell | Zendy

Open Access

Acrylamide and Glycidamide Hemoglobin Adducts and Epithelial Ovarian Cancer: A Nested Case–Control Study in Nonsmoking Postmenopausal Women from the EPIC Cohort

Author(s) -

Mireia ObónSantacana,

Leila LujánBarroso,

Ruth C. Travis,

Heinz Freisling,

Pietro Ferrari,

Gianluca Severi,

Laura Baglietto,

MarieChristine BoutronRuault,

Renée T. Fortner,

Jennifer Ose,

Heiner Boeing,

Virginia Menéndez,

Emilio SánchezCantalejo,

Saioa Chamosa,

José María Huerta,

Eva Ardanáz,

KayTee Khaw,

Nicholas J. Wareham,

Melissa A. Merritt,

Marc J. Gunter,

Antonia Trichopoulou,

EleniMaria Papatesta,

Eleni Klinaki,

Calogero Saieva,

Giovanna Tagliabue,

Rosario Tumino,

Carlotta Sacerdote,

Amalia Mattiello,

H. B. Bueno-de-Mesquita,

Petra H. Peeters,

N. Charlotte OnlandMoret,

Annika Idahl,

Eva Lundin,

Elisabete Weiderpass,

Hubert W. Vesper,

Elio Ríboli,

Eric J. Duell

Publication year - 2015

Publication title -

cancer epidemiology biomarkers and prevention

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.234

H-Index - 192

eISSN - 1538-7755

pISSN - 1055-9965

DOI - 10.1158/1055-9965.epi-15-0822

Subject(s) - nested case control study , medicine , serous fluid , acrylamide , cohort study , european prospective investigation into cancer and nutrition , case control study , epidemiology , oncology , gynecology , chemistry , organic chemistry , copolymer , polymer

Acrylamide was classified as "probably carcinogenic to humans (group 2A)" by the International Agency for Research on Cancer. Epithelial ovarian cancer (EOC) is the fourth cause of cancer mortality in women. Five epidemiological studies have evaluated the association between EOC risk and dietary acrylamide intake assessed using food frequency questionnaires, and one nested case-control study evaluated hemoglobin adducts of acrylamide (HbAA) and its metabolite glycidamide (HbGA) and EOC risk; the results of these studies were inconsistent.

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