Association of Prostate Cancer Risk Variants with Gene Expression in Normal and Tumor Tissue | Zendy

Kathryn L. Penney | Zendy; Jennifer A. Sinnott | Zendy; Svitlana Tyekucheva | Zendy; Travis Gerke | Zendy; Irene M. Shui | Zendy; Peter Kraft | Zendy; Howard D. Sesso | Zendy; Matthew L. Freedman | Zendy; Massimo Loda | Zendy; Lorelei A. Mucci | Zendy; Meir J. Stampfer | Zendy

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Association of Prostate Cancer Risk Variants with Gene Expression in Normal and Tumor Tissue

Author(s) -

Kathryn L. Penney,

Jennifer A. Sinnott,

Svitlana Tyekucheva,

Travis Gerke,

Irene M. Shui,

Peter Kraft,

Howard D. Sesso,

Matthew L. Freedman,

Massimo Loda,

Lorelei A. Mucci,

Meir J. Stampfer

Publication year - 2014

Publication title -

cancer epidemiology biomarkers and prevention

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.234

H-Index - 192

eISSN - 1538-7755

pISSN - 1055-9965

DOI - 10.1158/1055-9965.epi-14-0694-t

Subject(s) - prostate cancer , gene , genome wide association study , biology , single nucleotide polymorphism , genetics , cancer , snp , genetic association , prostate , cancer research , genotype

Numerous germline genetic variants are associated with prostate cancer risk, but their biologic role is not well understood. One possibility is that these variants influence gene expression in prostate tissue. We therefore examined the association of prostate cancer risk variants with the expression of genes nearby and genome-wide.

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