Genetic Mouse Models of Alzheimer′s Disease
Author(s) -
Yann S. Mineur,
Declan M. McLoughlin,
Wim E. Crusio,
Frans Sluyter
Publication year - 2005
Publication title -
neural plasticity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.288
H-Index - 68
eISSN - 2090-5904
pISSN - 1687-5443
DOI - 10.1155/np.2005.299
Subject(s) - disease , neuroscience , alzheimer's disease , genetic model , animal model , biology , psychology , medicine , genetics , gene , pathology , endocrinology
In the current minireview, we focus on genetic mouse models of Alzheimer's disease (AD). Because various excellent, up-to-date reviews, special issues, and reliable websites are already dedicated to the genetics of Alzheimer's disease in general and of animal models in particular, this review is not meant to be comprehensive. Rather, we aim to steer the Alzheimer's novice through the recent mouse literature on AD. Special attention will be paid to genetic models that have been tested behaviorally.
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