Open AccessDeficits in Beam‐Walking After Neonatal Motor Cortical Lesions are not Spared by Fetal Cortical Transplants in Rats
Author(s) -
Rand S. Swenson,
Erik Hvid Danielsen,
B. S. Klausen,
E. Erlich,
Jens Zimmer,
Anthony J. Castro
Publication year - 1989
Publication title -
neural plasticity
Language(s) - English
Resource type - Journals
eISSN - 2090-5904
pISSN - 1687-5443
DOI - 10.1155/np.1989.129
Subject(s) - lesion , motor cortex , hindlimb , medicine , fetus , cortex (anatomy) , neuroscience , anatomy , psychology , biology , pathology , pregnancy , genetics , stimulation
Adult rats that sustained unilateral motor cortical lesions at birth demonstrated deficits in traversing an elevated narrow beam. These deficits, manifested by hindlimb slips off the edge of the beam, were not spared in animals that received fetal cortical transplants into the lesion cavity immediately after lesion placement.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom