Open AccessDistribution of Copper in Rats Submitted to Treatment With Copper Aspirinate
Author(s) -
Weiping Liu,
Yikun Yang,
Huizhou Xiong,
Ying Lu,
Rong Yang
Publication year - 1998
Publication title -
metal-based drugs
Language(s) - English
Resource type - Journals
ISSN - 0793-0291
DOI - 10.1155/mbd.1998.333
Subject(s) - copper , distribution (mathematics) , metallurgy , environmental science , materials science , mathematics , mathematical analysis
The distribution of copper in Sprague - Dawley rats following a three month oral administration of 0,10 or 50mg/kg copper aspirinate has been investigated. Metal content was determined by ICP - AES in blood, brain, kidney, liver, lung, spleen, and dejection. The results show that treatment with copper aspirinate did not cause accumulation of copper in rats and excess ingested copper was excreted through feces.
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