Open AccessDi‐n‐Butyl‐, Tri‐n‐Butyl‐ and Triphenyltin dl‐Terebates: Synthesis, Characterization and In Vitro Antitumour Activity
Author(s) -
Marcel Gielen,
Huairang Ma,
Abdeslam Bouhdid,
Hassan Dalil,
Monique Biesemans,
Rudolph Willem
Publication year - 1997
Publication title -
metal-based drugs
Language(s) - English
Resource type - Journals
ISSN - 0793-0291
DOI - 10.1155/mbd.1997.193
Subject(s) - carboplatin , in vitro , chemistry , doxorubicin , pharmacology , microbiology and biotechnology , chemotherapy , biochemistry , biology , genetics , cisplatin
Di-n-butyltin, tri-n-butyltin and triphenyltin terebates were screened against several human tumour cell lines and found comparably or more active than carboplatin, cis-platin, 5-fluorouracil, methotrexate and doxorubicin, some reference compounds used clinically.
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