Open AccessOctreotide, a Somatostatin Analogue, Fails to Inhibit Hypoxia-induced Retinal Neovascularization in the Neonatal Rat
Author(s) -
Edward Averbukh,
Michael Halpert,
Ravit Yanko,
L. Yanko,
Jacob Pe’er,
Samuel Levinger,
Allan Flyvbjerg,
Itamar Raz
Publication year - 1999
Publication title -
journal of diabetes research
Language(s) - English
Resource type - Journals
eISSN - 2314-6753
pISSN - 2314-6745
DOI - 10.1155/edr.2000.39
Subject(s) - octreotide , somatostatin , hypoxia (environmental) , neovascularization , retinal , endocrinology , medicine , angiogenesis , chemistry , pharmacology , ophthalmology , organic chemistry , oxygen
Octreotide, a somatostatin analogue, has been shown to prevent angiogenesis in diverse in vitro models. We evaluated its effect on retinal neovascularization in vivo, using a neonatal rat retinopathy model.
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