Open AccessCorrosive Effect of Nifedipine in the Upper Gastrointestinal Tract
Author(s) -
Alexandra Lavy
Publication year - 1999
Publication title -
diagnostic and therapeutic endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.158
H-Index - 24
eISSN - 1029-0516
pISSN - 1026-714X
DOI - 10.1155/dte.6.39
Subject(s) - nifedipine , medicine , gastrointestinal tract , ingestion , gastric mucosa , gastroenterology , drug , stomach , pharmacology , calcium
Upper gastrointestinal tract mucosa is prone to injury. Drugs may disturb gastric mucosa protective mechanisms and cause damage. Injury by NSAIDs is a well described complication. Nifedipine, a widely used drug, was not described before as having a potential to damage gastrointestinal mucosa. We describe here, two patients, who developed esophageal and gastric mucosal damage, probably related to Nifedipine ingestion.
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