Structural Features of Antitumor Titanium Agents andRelated Compounds | Zendy

Francesco Caruso | Zendy; Miriam Rossi | Zendy; Cristian Opazo | Zendy; Claudio Pettinari | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Structural Features of Antitumor Titanium Agents andRelated Compounds

Author(s) -

Francesco Caruso,

Miriam Rossi,

Cristian Opazo,

Claudio Pettinari

Publication year - 2005

Publication title -

bioinorganic chemistry and applications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.865

H-Index - 35

eISSN - 1565-3633

pISSN - 1687-479X

DOI - 10.1155/bca.2005.317

Subject(s) - gastrointestinal tract , chemistry , titanium , combinatorial chemistry , stereochemistry , biology , pharmacology , computational biology , crystallography , cancer research , biochemistry , organic chemistry

Previous studies established some Ti compounds as having marked activity against tumors of the gastrointestinal tract and lack of side effects common to widely used cytostatic agents. We describe pertinent structural features of known antitumor Ti agents and other potentially active compounds. Particularly noteworthy features are that Ti-O bonds are short and Ti-O-Ti bond angles are large, demonstrating that in these compounds the O binding has high s-character approaching sp hybridization.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research