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Purpose. The purpose of this study is to analyze the effect of preoperative waiting time on the short-term outcomes and prognosis in colorectal cancer (CRC) patients. Methods. We retrospectively analyzed 3744 CRC patients who underwent primary CRC surgery at a single clinical medical center from Jan 2011 to Jan 2020. The baseline information, short-term outcomes, overall survival (OS), and disease-free survival (DFS) were compared among the short-waiting group, the intermediate-waiting group, and the long-waiting group. Results. A total of 3744 eligible CRC patients were enrolled for analysis. There were no significant differences in all of the baseline information and short-term outcomes among the three groups. In multivariate analysis, older age (OS:  p = 0.000 , HR = 1.947, 95% CI = 1.631–2.324; DFS:  p = 0.000 , HR = 1.693, 95% CI = 1.445–1.983), advanced clinical stage (OS:  p = 0.000 , HR = 1.301, 95% CI = 1.161–1.457; DFS:  p = 0.000 , HR = 1.262, 95% CI = 1.139–1.400), overall complications (OS:  p = 0.000 , HR = 1.613, 95% CI = 1.303–1.895; DFS:  p = 0.000 , HR = 1.560, 95% CI = 1.312–1.855), and major complications (OS:  p = 0.001 , HR = 1.812, 95% CI = 1.338–2.945; DFS:  p = 0.006 , HR = 1.647, 95% CI = 1.153–2.352) were independent factors of OS and DFS. In addition, no significant difference was found in all stages (OS,  p = 0.203 ; DFS,  p = 0.108 ), stage I (OS,  p = 0.419 ; DFS,  p = 0.579 ), stage II (OS,  p = 0.465 ; DFS,  p = 0.385 ), or stage III (OS,  p = 0.539 ; DFS,  p = 0.259 ) in terms of OS and DFS among the three groups. Conclusion. Preoperative waiting time did not affect the short-term outcomes or prognosis in CRC patients.

canadian journal of gastroenterology and hepatology

Does Preoperative Waiting Time Affect the Short-Term Outcomes and Prognosis of Colorectal Cancer Patients? A Retrospective Study from the West of China