Noncoding RNA as Diagnostic and Prognostic Biomarkers in Cerebrovascular Disease | Zendy

Ruiyuan Weng | Zendy; Zhiwen Jiang | Zendy; Yuxiang Gu | Zendy

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Noncoding RNA as Diagnostic and Prognostic Biomarkers in Cerebrovascular Disease

Author(s) -

Ruiyuan Weng,

Zhiwen Jiang,

Yuxiang Gu

Publication year - 2022

Publication title -

oxidative medicine and cellular longevity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.494

H-Index - 93

eISSN - 1942-0900

pISSN - 1942-0994

DOI - 10.1155/2022/8149701

Subject(s) - microrna , non coding rna , disease , medicine , long non coding rna , moyamoya disease , subarachnoid hemorrhage , pathophysiology , bioinformatics , diagnostic biomarker , biomarker , ischemic stroke , rna , pathology , biology , ischemia , cancer , gene , genetics

Noncoding RNAs (ncRNAs), such as microRNAs, long noncoding RNAs, and circular RNAs, play an important role in the pathophysiology of cerebrovascular diseases (CVDs). They are effectively detectable in body fluids, potentially suggesting new biomarkers for the early detection and prognosis of CVDs. In this review, the physiological functions of circulating ncRNAs and their potential role as diagnostic and prognostic markers in patients with cerebrovascular diseases are discussed, especially in acute ischemic stroke, subarachnoid hemorrhage, and moyamoya disease.

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