Antimycotic Activity of Some Medicinal Plants against Mucor circinelloides | Zendy

Renu Jangid | Zendy; Tahira Begum | Zendy

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Antimycotic Activity of Some Medicinal Plants against Mucor circinelloides

Author(s) -

Renu Jangid,

Tahira Begum

Publication year - 2022

Publication title -

biomed research international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.772

H-Index - 126

eISSN - 2314-6141

pISSN - 2314-6133

DOI - 10.1155/2022/3523920

Subject(s) - mucor circinelloides , catharanthus roseus , lantana camara , traditional medicine , biology , mauritiana , medicinal plants , mucor , botany , fungus , aloe vera , penicillium , ziziphus , medicine

The in vitro antimycotic activity of the leaf extract of Catharanthus roseus, Lantana camara, Nerium indicum, Sida cordifolia, and Ziziphus mauritiana was studied against M. circinelloides. This fungal species causes mucormycosis (black fungus). Presently, mucormycosis is affecting COVID patients due to prolonged use of steroids. So, it is needed to require development of more effective and less toxic antimycotic agents for the treatment of mucormycosis. Plants and their extraction preparations have been used as medicine against infectious disease. In this research, aqueous, ethanol, and DMSO (dimethyl sulfoxide) leaf extracts were used for antimycotic activity. All leaf extracts of selected medicinal plants recorded significant activity against M. circinelloides. Ethanol leaf extract of C. roseus showed the highest antimycotic activity followed by N. indicum and L. camara. Z. mauritiana which showed moderate activity against M. circinelloides.

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