A Case Report of Steroid-Resistant Cryptogenic Organizing Pneumonia Managed with Intravenous Immunoglobulins | Zendy

Christian Akem Dimala | Zendy; Urvi Patel | Zendy; Benjamin Lloyd | Zendy; Anthony A. Donato | Zendy; William Kimmel | Zendy; Robert W. Hallowell | Zendy; Caitlyn Moss | Zendy

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A Case Report of Steroid-Resistant Cryptogenic Organizing Pneumonia Managed with Intravenous Immunoglobulins

Author(s) -

Christian Akem Dimala,

Urvi Patel,

Benjamin Lloyd,

Anthony A. Donato,

William Kimmel,

Robert W. Hallowell,

Caitlyn Moss

Publication year - 2021

Publication title -

case reports in pulmonology

Language(s) - English

Resource type - Journals

eISSN - 2090-6846

pISSN - 2090-6854

DOI - 10.1155/2021/9343491

Subject(s) - medicine , intravenous immunoglobulins , etiology , chest radiograph , pneumonia , antibiotics , cryptogenic organizing pneumonia , antibody , emergency department , intravenous antibiotics , surgery , lung , gastroenterology , immunology , psychiatry , microbiology and biotechnology , biology

Fewer than ten reported cases of cryptogenic organizing pneumonia (COP) have been managed with intravenous immunoglobulins (IVIg). We report a case of a 72-year-old man who presented with a worsening cough and diffuse opacities on chest radiograph. Following no improvement with antibiotics and negative complementary investigations for infectious, malignant, and autoimmune etiologies, COP was confirmed on lung biopsy. Due to continued clinical deterioration despite high-dose steroids and new severe steroid-induced hallucinations, the patient was placed on intravenous immunoglobulins (IVIg) and mycophenolate mofetil and made a satisfactory recovery. IVIg should be considered as an important steroid-sparing alternative in patients with COP.

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