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A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
Author(s) -
Dan Han,
YuQian Sun,
Rong Xie,
Xiaojian Zhu,
Zhaodong Zhong
Publication year - 2021
Publication title -
case reports in hematology
Language(s) - English
Resource type - Journals
eISSN - 2090-6560
pISSN - 2090-6579
DOI - 10.1155/2021/8878803
Subject(s) - medicine , covid-19 , methylprednisolone , septic shock , disease , transplantation , graft versus host disease , immunology , sepsis , infectious disease (medical specialty) , virology , outbreak
We report a case of coronavirus disease 2019 (COVID-19) after haploidentical transplantation with acute graft-versus-host disease (aGVHD). COVID-19 and aGVHD were improved under treatment with arbidol, remdesivir, methylprednisolone, and ruxolitinib. However, eventually, the patient died of septic shock and multiple organ failure. It was concluded that the disease condition of this COVID-19 patient after transplantation was serious, complex, and variable, with poor prognosis.

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