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Coincidence of Large Adrenal Cyst and Prominent Hyporeninemic Hyperaldosteronism
Author(s) -
Takaaki Sakaue,
Yosuke Okuno,
Kosuke Mukai,
Shingo Fujita,
Junji Kozawa,
Hitoshi Nishizawa,
Taka-aki Matsuoka,
Hiromi Iwahashi,
Norikazu Maeda,
Yuto Yamazaki,
Hironobu Sasano,
Michio Otsuki,
Iichiro Shimomura
Publication year - 2021
Publication title -
case reports in endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.26
H-Index - 6
eISSN - 2090-6501
pISSN - 2090-651X
DOI - 10.1155/2021/8860498
Subject(s) - medicine , hyperaldosteronism , pathological , primary aldosteronism , pathology , kidney , adrenal gland , aldosterone
A 67-year-old Japanese woman who had end-stage renal disease was referred to our hospital for kidney transplantation. Abdominal CT revealed a large adrenal mass with inhomogeneity. She had a history of hospitalization for stroke and heart failure and exhibited prominent hyporeninemic hyperaldosteronism. Histological examination of the resected tumor with anti-CYP11B2 antibody indicated that she had a vascular endothelial cyst with primary aldosteronism (PA) due to multiple adrenocortical micronodules. This report implicates the pathological interaction between adrenal vascular cysts and PA-mediated vascular damage of the adrenal vein.

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