An Update on the Potential of Mesenchymal Stem Cell Therapy for Cutaneous Diseases | Zendy

Yanyun Li | Zendy; Ziyu Ye | Zendy; W.J. Yang | Zendy; Qunzhou Zhang | Zendy; Jincheng Zeng | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

An Update on the Potential of Mesenchymal Stem Cell Therapy for Cutaneous Diseases

Author(s) -

Yanyun Li,

Ziyu Ye,

W.J. Yang,

Qunzhou Zhang,

Jincheng Zeng

Publication year - 2021

Publication title -

stem cells international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.205

H-Index - 64

eISSN - 1687-9678

pISSN - 1687-966X

DOI - 10.1155/2021/8834590

Subject(s) - mesenchymal stem cell , regeneration (biology) , stem cell , medicine , stem cell therapy , stromal cell , clinical trial , cell therapy , immune system , regenerative medicine , inflammation , immunology , bioinformatics , cancer research , pathology , biology , microbiology and biotechnology

Mesenchymal stem or stromal cells (MSCs) are nonhematopoietic postnatal stem cells with self-renewal, multipotent differentiation, and potent immunomodulatory and anti-inflammatory capabilities, thus playing an important role in tissue repair and regeneration. Numerous clinical and preclinical studies have demonstrated the potential application of MSCs in the treatment of tissue inflammation and immune diseases, including inflammatory skin diseases. Therefore, understanding the biological and immunological characteristics of MSCs is important to standardize and optimize MSC-based regenerative therapy. In this review, we highlight the mechanisms underlying MSC-mediated immunomodulation and tissue repair/regeneration and present the latest development of MSC-based clinical trials on cutaneous diseases.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research