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The purpose of this study was to analyze the hemodynamic changes and nursing care of patients with colorectal cancer who were peripherally placed into the central venous catheter (PICC) by color Doppler ultrasound based on an optimized algebraic reconstruction (ART) (OART) algorithm. In this study, 150 patients with colorectal cancer were selected and randomly divided into observation group and control group, with 75 cases in each group. Different nursing interventions were carried out. An optimized algebraic reconstruction (OART) algorithm was proposed, and the traditional ART algorithm and filtered back-projection (FBP) algorithm were introduced for comparison. They were applied in ultrasounds of 150 colorectal cancer patients undergoing PICC. The results showed that the Dice coefficient (Dice) and peak signal-to-noise ratio (PSNR) of the OART algorithm were greater than those of the ART and FBP algorithms, while the difference function (DF) and the running time were opposite ( P  &lt; 0.05). The blood flow velocity (BFV) and blood flow (BF) of the arm vein 5 days after puncture were the least, which were less than those before puncture and 10 days and 30 days after puncture ( P  &lt; 0.05). Thrombosis was most likely to be found 4–6 days after puncture (28 cases), followed by 10–15 days after puncture (22 cases), and one day after the puncture (19 cases). The BFV and BF of patients with thrombosis were lower than those of patients without thrombosis ( P  &lt; 0.05). The total infection rate of PICC in the observation group was 10.7%, which was lower than that in the control group 32.0%,  P  &lt; 0.05. Nursing satisfaction of patients in observation group and control group was 95.99% and 75.99%, respectively,  P  &lt; 0.05, and the difference was statistically significant. In short, the ORAT algorithm proposed had better performance than the traditional algorithms in ultrasound image reconstruction; strengthening nursing intervention for chemotherapy patients with colorectal cancer undergoing PICC could effectively reduce the infection rate of PICC and improve the nursing satisfaction of patients.

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Optimized Algebraic Reconstruction Algorithm Based Hemodynamic Changes in Color Doppler Ultrasound in Monitoring the Patients with Colorectal Cancer Undergoing Peripherally Inserted Central Catheter and Catheterization Nursing