Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine Moiety | Zendy

Xuetong Yu | Zendy; Wenjun Lan | Zendy; Meihang Chen | Zendy; Su Xu | Zendy; Xiaoxi Luo | Zendy; Shuhong He | Zendy; Haijiang Chen | Zendy; Qiang Fei | Zendy; Wenneng Wu | Zendy

Open Access

Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine Moiety

Author(s) -

Xuetong Yu,

Wenjun Lan,

Meihang Chen,

Su Xu,

Xiaoxi Luo,

Shuhong He,

Haijiang Chen,

Qiang Fei,

Wenneng Wu

Publication year - 2021

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.436

H-Index - 50

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2021/8370407

Subject(s) - mythimna separata , botrytis cinerea , botryosphaeria dothidea , chemistry , moiety , antifungal , spodoptera , alternaria solani , stereochemistry , fungicide , botany , lepidoptera genitalia , microbiology and biotechnology , biochemistry , biology , gene , recombinant dna

Seventeen novel N-phenylbenzamide derivatives bearing a trifluoromethylpyrimidine moiety were synthesized via four-step reactions. Their antifungal and insecticidal properties were evaluated. Antifungal test results demonstrated that some of the synthesized compounds showed better in vitro bioactivities against Phomopsis sp., Botryosphaeria dothidea (B. dothidea), and Botrytis cinerea (B. cinerea) at 50 μg/mL than pyrimethanil. Unfortunately, the synthesized compounds revealed lower insecticidal activities against Spodoptera frugiperda (S. frugiperda) and Mythimna separata (M. separata) at 500 μg/mL than chlorantraniliprole.

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