The Effects of Chinese Herbal Decoction Combined with Recombinant Human Interferon α2b on MRI Imaging, Tumor Markers, and Immune Function in Patients with Renal Cell Carcinoma | Zendy

Siliang Song | Zendy; Wen Li | Zendy; Wenjuan Liang | Zendy; Tian Xiu | Zendy

Open Access

The Effects of Chinese Herbal Decoction Combined with Recombinant Human Interferon α2b on MRI Imaging, Tumor Markers, and Immune Function in Patients with Renal Cell Carcinoma

Author(s) -

Siliang Song,

Wen Li,

Wenjuan Liang,

Tian Xiu

Publication year - 2021

Publication title -

evidence-based complementary and alternative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.552

H-Index - 90

eISSN - 1741-4288

pISSN - 1741-427X

DOI - 10.1155/2021/8106974

Subject(s) - decoction , medicine , renal cell carcinoma , traditional chinese medicine , immune system , interferon , immunotherapy , clinical efficacy , recombinant dna , cd8 , oncology , gastroenterology , immunology , pathology , biology , biochemistry , alternative medicine , gene

Background To explore the clinical efficacy of traditional Chinese medicine decoction combined with recombinant human interferon α 2b in the treatment of renal cell carcinoma (RCC).Methods 68 RCC patients were divided into the control group and treatment group ( n = 34). The control group was treated with recombinant human interferon α 2b, and the treatment group was treated with traditional Chinese medicine decoction on the basis of the control group. The clinical efficacy and life quality were observed. At the same time, the changes of immune function before and after treatment were compared.Results After one course of treatment, the effective rate and clinical benefit rate of the treatment group were higher than those of the control group. The Karnofsky score in the treatment group was better than that in the control group. In improving the immune function, the treatment group was better than the control group in increasing CD3+ and CD4+ and reducing CD8+.Conclusion Traditional Chinese medicine decoction combined with recombinant human interferon α 2b has a good effect on the treatment of RCC. It can not only improve the common clinical symptoms of patients but also improve the quality of life and cellular immune function of patients.

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