Open AccessEffect of Antioxidants in the Treatment of COPD Patients: Scoping Review
Author(s) -
Mauricio Orozco-Levi,
Claudia Carolina Colmenares-Mejía,
Jéssica Cristina Ruiz,
Yurley Dayanna Valencia-Barón,
Alba Ramírez-Sarmiento,
Doris Cristina Quintero-Lesmes,
Norma C. Serrano
Publication year - 2021
Publication title -
journal of nutrition and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.789
H-Index - 42
eISSN - 2090-0732
pISSN - 2090-0724
DOI - 10.1155/2021/7463391
Subject(s) - medicine , copd , acetylcysteine , intensive care medicine , psychological intervention , disease , oxidative stress , lung function , medline , nutritional supplementation , physical therapy , antioxidant , lung , nursing , biochemistry , chemistry , political science , law
Chronic obstructive pulmonary disease (COPD) is a common, preventable, treatable lung disease characterized by persistent respiratory symptoms and airflow limitation and multiorgan impact. This affects the nutritional status of patients and requires multidimensional interventions including nutritional interventions according to individual metabolic needs. Our scoping review determined the effects of antioxidants in the treatment of COPD patients and their role in the decrease in the probability of exacerbations, hospital readmissions, and changes in lung function. The sources MEDLINE, LILACS, and Google Scholar were consulted and 19 studies were selected. The most indicated antioxidants are N-Acetylcysteine, vitamins E and D, and Zinc. Other antioxidants from plants or fruits extracts are also being investigated. The beneficial effect of antioxidants in stable or exacerbated patients is not clear, but theoretical and biological arguments of benefit justify lines of research that specify the impact on reducing oxidative stress and negative effects in COPD.