Opioid Overdose and Serotonin Syndrome due to Gastric Bezoar in a Woman with Autism and Pica Behaviour | Zendy

Iolanda Palimaru | Zendy; M. Guetta | Zendy; Cora Cravero | Zendy; Clémence Fron | Zendy; David Cohen | Zendy; Marianna Giannitelli | Zendy

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Opioid Overdose and Serotonin Syndrome due to Gastric Bezoar in a Woman with Autism and Pica Behaviour

Author(s) -

Iolanda Palimaru,

M. Guetta,

Cora Cravero,

Clémence Fron,

David Cohen,

Marianna Giannitelli

Publication year - 2021

Publication title -

case reports in psychiatry

Language(s) - English

Resource type - Journals

eISSN - 2090-682X

pISSN - 2090-6838

DOI - 10.1155/2021/7334467

Subject(s) - medicine , tramadol , bezoar , pica (typography) , anesthesia , serotonin syndrome , autism , (+) naloxone , fluoxetine , opioid , psychiatry , analgesic , serotonin , serotonergic , receptor , world wide web , computer science

We are presenting the case of a 38-year-old woman with nonverbal autism and intellectual disability, hospitalized in a neurobehavioural unit because of a pica behaviour for 3 years. During the hospitalization, the patient presented an episode of pain, agitation, restlessness, rhabdomyolysis, coma, tachycardia, hyperthermia, shivering, and diarrhoea. The main hypothesis raised was tramadol overdose because of the immediate antidote response to the injection of naloxone 0,4 mg/mL. Even if we did not exceed the recommended prescription dosage of tramadol, the presence of gastric bezoar slowed the absorption of the drug, and the consequence was an opioid overdose and serotonin syndrome.

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