trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction | Zendy

Zhuo Sun | Zendy; Jinbo Fan | Zendy; Yufeng Zhao | Zendy

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trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction

Author(s) -

Zhuo Sun,

Jinbo Fan,

Yufeng Zhao

Publication year - 2021

Publication title -

genetics research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.301

H-Index - 71

eISSN - 1469-5073

pISSN - 0016-6723

DOI - 10.1155/2021/6683460

Subject(s) - heterochromatin , histone , chromatin , chromosome , genetics , x chromosome , biology , dna , microbiology and biotechnology , gene

During X chromosome inactivation, many chromatin changes occur on the future inactive X chromosome, including acquisition of a variety of repressive covalent histone modifications, heterochromatin protein associations, and DNA methylation of promoters. Here, we summarize trans -acting factors and cis elements that have been shown to be involved in the human inactive X chromosome organization and compaction.

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