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Objectives   This study aimed to evaluate denture cleanser effects on color stability, surface roughness, and hardness of PMMA denture base resin reinforced with nano-ZrO 2 .Materials and Methods   A total of 420 specimens were fabricated of unreinforced and nano-ZrO 2  reinforced acrylic resin at 2.5% and 5%, resulting in 3 main groups. These groups were further subdivided ( n  = 10) according to immersion solution (distilled water, Corega, sodium hypochlorite, and Renew) and immersion duration. Surface roughness, hardness, and color were measured at baseline (2 days- T  0 ) in distilled water and then after 180 and 365 days of immersion ( T  1  &  T  2 ) in water or denture cleansing solutions. Data was collected and analyzed using two-way ANOVA followed by Bonferroni post hoc test ( α  = 0.05).Results   Surface roughness increased significantly after denture cleanser immersion of unmodified and nano-ZrO 2 -modified PMMA materials while hardness decreased ( P  < 0.001). The denture cleansers significantly affected the color of both PMMA denture bases ( P  < 0.001). The immersion time in denture cleansers significantly affected all tested properties ( P  < 0.001). Within denture cleansers, NaOCl showed the highest adverse effects ( P  < 0.05) while Renew showed the least adverse effects.Conclusion   Denture cleansers can significantly result in color change and alter the surface roughness and hardness of denture base resin even with ZrO 2  nanoparticles addition. Therefore, they should be carefully used.

Color Stability and Surface Properties of PMMA/ZrO2 Nanocomposite Denture Base Material after Using Denture Cleanser