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Gut-Lung Axis in COVID-19
Author(s) -
Imane Allali,
Youssef Bakri,
Saaïd Amzazi,
Hassan Ghazal
Publication year - 2021
Publication title -
interdisciplinary perspectives on infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.593
H-Index - 28
eISSN - 1687-7098
pISSN - 1687-708X
DOI - 10.1155/2021/6655380
Subject(s) - microbiome , lung , covid-19 , gut microbiome , medicine , immunology , immunity , respiratory system , coronavirus , host (biology) , pandemic , virology , biology , immune system , bioinformatics , pathology , disease , genetics , infectious disease (medical specialty)
COVID-19 is a pandemic infection of the respiratory system caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The viral ribonucleic acid (RNA) was found in many parts of the COVID-19 patients including the stool, suggesting a potential interaction with the host's gut microbiome. The gut microbiome also plays major roles in immunity and inflammation. It also impacts pulmonary functions through the gut-lung axis. There have been recent reports of the importance of the host microbiome in infection and pathogenicity. The understanding of the gut and lung microbiomes would open the gate to new therapeutic approaches.

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