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The study was aimed to explore the segmentation effects of different algorithms on thyroid nodule ultrasound images, so as to better protect the recurrent laryngeal nerve during thyroid surgery. Specifically, 186 patients with thyroid nodules were selected as the research objects. The segmentation performances of the gradient vector flow (GVF) Snake, Watershed, and Snake algorithms were compared from 6 aspects of image segmentation effects, pixel accuracy (PA), Intersection over Union (IOU) value, algorithm running time, postoperative recurrent laryngeal nerve injury, intraoperative bleeding volume, and postoperative drainage volume. It was found that the average PA value (0.954) and the IOU value (0.866) of the GVF Snake algorithm were obviously higher than those of the other two algorithms. The total incidence of recurrent laryngeal nerve injury based on the GVF Snake algorithm (4.69%) was obviously lower than that of the Snake algorithm (19.35%) and the watershed algorithm (16.13%). The bleeding volume and postoperative drainage volume based on the GVF Snake algorithm were less versus the other two algorithms ( P &lt; 0.05 ). In conclusion, the GVF Snake algorithm demonstrates ideal segmentation effects, which is suggested in the treatment of thyroid nodules to better protect the recurrent laryngeal nerve.

Edge Segmentation Algorithm‐Based Prevention of Recurrent Laryngeal Nerve Injury in Treatment of Thyroid Nodules Using Ultrasound Images