Autoinflammatory/Autoimmunity Syndrome Induced By Adjuvants (ASIA) Due to Silicone Incompatibility Syndrome | Zendy

Génessis Maldonado | Zendy; Roberto Peña Guerrero | Zendy; María Intriago | Zendy; Carlos Ríos | Zendy

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Autoinflammatory/Autoimmunity Syndrome Induced By Adjuvants (ASIA) Due to Silicone Incompatibility Syndrome

Author(s) -

Génessis Maldonado,

Roberto Peña Guerrero,

María Intriago,

Carlos Ríos

Publication year - 2021

Publication title -

case reports in rheumatology

Language(s) - English

Resource type - Journals

eISSN - 2090-6889

pISSN - 2090-6897

DOI - 10.1155/2021/5595739

Subject(s) - silicone , adjuvant , medicine , anti nuclear antibody , autoimmunity , dermatology , immunology , antibody , autoantibody , chemistry , organic chemistry

The adjuvant-induced autoimmune syndrome (ASIA) is associated with a dysregulation of the innate and adaptive immune system after exposure to chemical compounds, including liquid paraffin, silicone gel, acrylamides, and hyaluronic acid. Due the increase of the use of these compounds in cosmetic procedures, the prevalence of this syndrome is increasing. We present the first report in Ecuador associated to ASIA after an elective silicone breast prosthesis procedure, manifested as polyarthralgia, positive antinuclear antibody, anticentromere antibody, and a moderate positive Sclero-70.

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