Atypical Nodular Pulmonary Kappa Light-Chain Deposition | Zendy

Jessy A. Nellipudi | Zendy; John Brealey | Zendy; Sonja Klebe | Zendy; David Lance | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Atypical Nodular Pulmonary Kappa Light-Chain Deposition

Author(s) -

Jessy A. Nellipudi,

John Brealey,

Sonja Klebe,

David Lance

Publication year - 2021

Publication title -

case reports in pathology

Language(s) - English

Resource type - Journals

eISSN - 2090-6781

pISSN - 2090-679X

DOI - 10.1155/2021/5578885

Subject(s) - kappa , immunoglobulin light chain , lesion , pathology , medicine , malignancy , eosinophilic , stain , staining , antibody , immunology , philosophy , linguistics

We report a case of an incidental positron emission tomography avid right middle lobe lesion which was increasing in size. Due to concerns regarding malignancy, the patient underwent right middle lobectomy. Microscopic examination showed a 12 × 10 × 10 mm poorly circumscribed lesion composed of eosinophilic material. The material labelled strongly for kappa light chains; however, Congo red stain was only weakly positive and without “apple-green” positive birefringence under polarised light. Electron microscopy revealed fibrillar amyloid-like material. The features were those of kappa light-chain deposition.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research