The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors | Zendy

Jiajie Tu | Zendy; Huan Yang | Zendy; Lei Jiang | Zendy; Yu Chen | Zendy; Zhe Li | Zendy; Lei Li | Zendy; Yuanyuan Zhang | Zendy; Xiaochun Chen | Zendy; He Chen | Zendy; Zhiying Yu | Zendy

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The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors

Author(s) -

Jiajie Tu,

Huan Yang,

Lei Jiang,

Yu Chen,

Zhe Li,

Lei Li,

Yuanyuan Zhang,

Xiaochun Chen,

He Chen,

Zhiying Yu

Publication year - 2021

Publication title -

international journal of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.875

H-Index - 60

eISSN - 1687-8345

pISSN - 1687-8337

DOI - 10.1155/2021/5572063

Subject(s) - estrogen , microrna , long non coding rna , medicine , small nucleolar rna , non coding rna , bioinformatics , female reproductive system , rna , gene , reproductive system , cancer research , biology , computational biology , genetics

The pathogenesis of ovarian and endometrial cancers is closely associated with estrogen-related pathways. These estrogen-dependent tumors seriously threaten the health and quality of life in women. Noncoding RNAs (ncRNAs) are defined as RNAs that do not encode proteins, including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), both of which have been reported in estrogen-dependent female reproductive system tumors. This review systematically summarizes the role of ncRNAs in estrogen-dependent tumors and common patterns of regulatory mechanisms to explore their future research directions in tumor diagnosis, treatment, and prognosis. This may provide new ideas for the potential application of ncRNAs in estrogen-dependent female reproductive system tumors.

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