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Clostridium perfringens  is a rare cause of septic shock, occurring most frequently in immunocompromised patients. An uncommon cause of  Clostridium perfringen  septicemia is spontaneous gangrenous gas necrosis of the spleen, where the primary treatment is splenectomy. We present a case of septic shock caused by spontaneous gangrenous gas necrosis of the spleen secondary to  Clostridium perfringens  in a patient whose profound pancytopenia made obtaining definitive source control extremely difficult.

Septic Shock and Spontaneous Gangrenous Gas Necrosis of the Spleen Secondary to Clostridium perfringens: The Importance of Source Control