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Update in the Management of ANCA-Associated Vasculitis: Recent Developments and Future Perspectives
Author(s) -
Karla N. Samman,
Carolyn Ross,
Christian Pagnoux,
JeanPaul Makhzoum
Publication year - 2021
Publication title -
international journal of rheumatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.8
H-Index - 33
eISSN - 1687-9279
pISSN - 1687-9260
DOI - 10.1155/2021/5534851
Subject(s) - microscopic polyangiitis , anca associated vasculitis , granulomatosis with polyangiitis , medicine , limiting , vasculitis , intensive care medicine , pathology , disease , engineering , mechanical engineering
Significant progress has been made in the treatment of ANCA-associated vasculitides (AAV), notably in granulomatosis with polyangiitis and microscopic polyangiitis. Over the past few years, many innovative studies have changed the way we now induce and maintain remission in AAV; achieving remission while limiting treatment toxicity is the key. This article provides an in-depth, up-to-date summary of recent trials and suggests treatment algorithms for induction and maintenance of remission based on the latest guidelines. Future possible therapies in AAV will also be discussed.

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